AestheticsSex & FertilitySubcutaneous

Melanotan I

Typical Dose

0.5–1 mg

Frequency

Daily during loading

Half-Life

~30-60 minutes

Research-use dosing; specific study population not established.

Melanotan I Overview

Mechanism of Action

Melanotan I (afamelanotide) is a synthetic alpha-MSH analog that stimulates melanogenesis via MC1R activation, promoting skin pigmentation and photoprotection.

Half-Life

~30-60 minutes

Timing

Any time

Alternatives in this class

Same mechanism as Melanotan I — use as an alternative, not combined together.

  • Melanotan II

Melanotan I Dosing Protocol

Loading

0.5-1 mg/day

Maintenance

0.5-1 mg

Melanotan I Expected Timeline

No timeline data available.

Melanotan I Side Effects

Nausea

Facial flushing

Injection site irritation

Melanotan I Research Studies

No studies referenced.

Melanotan I FAQ

How is Melanotan I different from Melanotan II?

MT-I is more selective for MC1R (tanning), while MT-II also activates MC3R/MC4R (sexual function).

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