Tirzepatide Overview
Mechanism of Action
Tirzepatide is a dual GIP and GLP-1 receptor agonist that enhances insulin secretion, suppresses appetite, slows gastric emptying, and promotes weight loss through complementary metabolic pathways.
Half-Life
~5 days
Timing
Same day each week
Alternatives in this class
Same mechanism as Tirzepatide — use as an alternative, not combined together.
- Semaglutide
- Retatrutide
Common Stacks
- B12
Tirzepatide Dosing Protocol
Titration
2.5 mg/week for 4 weeks, then increase
Maintenance
5-15 mg/week
Tirzepatide Expected Timeline
No timeline data available.
Tirzepatide Side Effects
Nausea
Diarrhea
Decreased appetite
Injection site reactions
Constipation
Tirzepatide Research Studies
No studies referenced.
Tirzepatide FAQ
How is Tirzepatide different from Semaglutide?
Tirzepatide targets both GIP and GLP-1 receptors, while Semaglutide targets only GLP-1.